BioRefineries Blog

Versión en Español Type of post: NEWS IN BRIEF. Ginkgo Bioworks and Sumitomo Chemical have announced a R&D collaboration program to develop more sustainable biobased chemicals for multiple industries. Press release: “ Ginkgo Bioworks Announces R&D Collaboration with Sumitomo Chemical to Develop More Sustainable Bio-Based Chemicals for Multiple Industries ”, 07/06/2021. Figure 1. Ginkgo and Sumitomo Chemical join forces to develop more sustainable biobased chemicals Sumitomo Chemical seeks to leverage Ginkgo's long-established expertise in organism engineering to significantly increase the production efficiency and sustainability of a key biobased commercial products. Sumitomo Chemical was founded around a mission to drive societal impact and solve environmental challenges through technology, and the company has chosen to leverage Ginkgo's extensive cell programming platform and biological codebase to explore next generation solutions as Sumitomo Chemical looks t...

Versión en Español Type of post: NEWS IN BRIEF. Lygos, Inc. has announced that it is working with the US Department of Energy Bioenergy Technologies Office’s Agile BioFoundry (ABF) to generate the largest multi-omics dataset for guiding the development of organic acids. Press release: “ Lygos and the Agile BioFoundry Generate Largest Multi-Omics Dataset to Accelerate Machine Learning Capabilities for Engineering Strains for Producing Organic Acids ”, 15/03/2021. Related posts: - “ Lygos validates a fermentation process for sustainable cannabinoids ”, 04/09/2020.  - “ Lygos is partnering with Flexible Solutions to advance biobased aspartic acid production technology ”, 17/02/2021. Figure 1. Agile BioFoundry and Lygos to generate a multi-omics dataset to improve biobased malonic acid production Over the course of the project, scientists will produce more than 500,000 data points from a series of experiments. ABF is now using its artificial neural networks to train machine l...

Versión en Español Type of post: NEWS IN BRIEF. DMC Biotechnologies (DMC) has successfully demonstrated the production at full commercial scale of its first product, the amino acid L-alanine. Press release: “ DMC Demonstrates Full Commercial Scale at Record Speed ”, 15/03/2021. Related post: “ DMC Biotech takes important step towards commercial production of L-alanine ”, 21/02/2020. Figure 1. EW Biotech facility (taken from the press release) The scale-up results identically tracked the performance at bench and pilot scales, further validating the predictability and scalability of DMC’s Dynamic Metabolic Control technology. Importantly, commercial performance metrics were demonstrated, meaning that no further strain improvements are required to achieve the target selling price. The scale-up process was conducted at EW Biotech’s facility (85 m3 fermentation) in Leuna (Germany).

Versión en Español Type of post: NEWS IN BRIEF.  Royal DSM and TU Delft have announced the establishment of the Artificial Intelligence Lab for Biosciences (the AI4B.io Lab). This laboratory will be the first of its kind in Europe to apply artificial intelligence (AI) to full-scale biomanufacturing, from microbial strain development to process optimization and scheduling.  Press release: “ DSM and TU Delft launch AI4B.io Lab ”, 11/01/2021.  Figure 1. DSM and TU Delft launch a lab to apply artificial intelligence to full-scale biomanufacturing  The AI4B.io Lab will be part of the Dutch National Innovation Center for AI (ICAI), which works to keep the Netherlands at the forefront of knowledge and talent development in AI. It will be led by Professor Marcel Reinders, Director TU Delft Bioengineering Institute. Although AI is already widely applied in engineering research, the AI4B.io Lab will be the first of its kind to explore AI’s potential in biosciences and bi...